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Cerebrolysin

≥99% Purity
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COA Included
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Categories: Neuropeptides

Cerebrolysin is a neuropeptide preparation of low-molecular-weight peptides and amino acids from porcine brain tissue. Studied for BDNF/NGF-like neurotrophic activity and synaptic plasticity research.


Cerebrolysin is a standardized, well-characterized neuropeptide preparation produced through controlled enzymatic proteolysis of purified porcine brain proteins. The resulting mixture consists of approximately 75% low-molecular-weight peptides (all below 10 kDa) and 25% free amino acids. The peptide fraction contains sequences with structural homology to endogenous neurotrophic factors, which is the basis for its extensive research applications in neuroscience. The standardized manufacturing process ensures batch-to-batch reproducibility of the peptide profile, confirmed by HPLC fingerprinting and amino acid composition analysis.

The neurotrophic factor-like activity of Cerebrolysin has been documented through multiple in vitro and in vivo research paradigms. Cell culture studies demonstrate that the preparation activates signaling pathways characteristic of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF), including PI3K/Akt-dependent neuronal survival signaling, MAPK/ERK-mediated neurite outgrowth, and CREB (cAMP response element-binding protein) phosphorylation. This multi-neurotrophic activity profile distinguishes Cerebrolysin from single-target research compounds and enables investigation of coordinated neurotrophic signaling.

Published research applications span a broad range of neuroscience paradigms: synaptic plasticity and long-term potentiation (LTP) studies, neurogenesis in hippocampal models, amyloid precursor protein (APP) processing and secretase modulation in Alzheimer’s disease models, neurotrauma and stroke recovery research, and developmental neurobiology. The preparation has been the subject of over 200 peer-reviewed publications and has been studied by neuroscience research groups worldwide.

Supplied as a ready-to-use solution (60mg per vial, 6 vials per kit). Store at 2-8°C protected from light. Do not freeze. For neuroscience research applications only.

⚠ Supplied strictly for research and experimental purposes only.